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KMID : 0616119820130020070
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Korean Journal of Pharmacognosy
1982 Volume.13 No. 2 p.70 ~ p.78
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Studies on the Efficacy of the Combined Preparation of Crude Drugs ( Ⅶ ) Effect of “ Saengkankunbi - Tang ”on the Liver Tissue Recovery
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홍남두/Hong ND
김종우/김병운/손정곤/Kim JW/Kim BW/Shon JG
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Abstract
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To investigate the effect of "Saengkankunbi-Tang" on the liver tissue recovery in about 70% cutted rat liver, the observation on the photographing by the Gammacamera and the electromicroscopic section against the rabbit liver induced by CCl₄, these studies were conducted. The results were summerized as follows; Observed on the liver tissue recovery, function regeneration and body weight increase in about 70 % cutted rat liver, the recovery of liver tissue and body weight were increased with the passage of the time and also they were showed to the high increase rate in proportion to administration amount. The glucose content in the serum was found in increasing tide as compared with the control group. The alkaline phosphate activity in the serum showed the significant difference in the 10th day and 13th day as compared with the control group. The ammonia content in the blood showed the significant difference only in the 10th day. Observed on the photographing by the Gamma-camera against the rabbit liver induced by CCl₄, sample groups were shown to be significant recovery as compared with the control group. Observed on the electromicroscopic section, sample groups showed the control action of the nuclear destruction against the rabbit liver induced by CCl₄ and also they showed the control action of the expansion of glycogen and granular endothelial reticulum in cytoplasm. According to the above finding, it is presume that "Saengkankunbi-Tang" can be applicable to the extensive treatment of liver disease.
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